Current Collaborations and Initiatives

Lupus Therapeutics has been involved in some of the most important breakthroughs in lupus research and is helping to guide future breakthroughs.

Current/Ongoing Partner Studies

Study Name: Abbvie SELECT-SLE

Phase 3, SLE

Active, Not Recruiting

Study Name: Biogen TOPAZ-1

Phase 3, SLE

Active, Not Recruiting

Study Name: Biogen TOPAZ-2

Phase 3, SLE

Active, Not Recruiting

Study Name: BMS Breakfree-SLE

Phase 2, SLE

Recruiting

Study Name: BMS POETYK-1 SLE

Phase 3, SLE

Active, Not Recruiting

Study Name: BMS POETYK-2 SLE

Phase 3, SLE

Active, Not Recruiting

Study Name: ELOWEN-1

Phase 3, SLE, CLE

Recruiting

Study Name: ELOWEN-2

Phase 3, SLE, CLE

Recruiting

Study Name: Genentech GA45767

Phase 1, SLE

Recruiting

Study Name: IMVT-1402-2701

Phase 2, CLE

Active, Not Recruiting

Study Name: Janssen GARDENIA-SLE

Phase 3, SLE

Recruiting

Study Name: Novartis CYTB323

Phase 2, SLE, LN

Recruiting

Study Name: Novartis SIRIUS SLE 1

Phase 3, SLE

Active, Not Recruiting

Study Name: Novartis SIRIUS SLE 2

Phase 3, SLE

Active, Not Recruiting

Study Name: UCB Phoenycs Fly

Phase 3, SLE

Recruiting

Study Name: Novartis SIRIUS LN

Phase 3, LN

Active, Not Recruiting

Study Name: Biogen AMETHYST

Phase 2/3, CLE

Recruiting

Study Name: Zenas BioPharma SunStone

Phase 2, SLE

Recruiting

Study Name: VIBRANT

Phase 2, LN

Recruiting

Current/Ongoing LRA-Sponsored Studies

Study Name: Lupus Landmark

Phase NA, SLE

Recruiting

Current Collaborations

AUTO1-SL2

Autologous Obecabtagene Autoleucel CAR T Therapy

Phase 2, LN

Clinical Services

BMS CAR-T

CD19-Targeted Nex-T Chimeric Antigen Receptor (CAR) T Cells

CA061-1001 Phase 1

Clinical Services

Cabaletta Bio CAR T Therapy

CABA-201, An Autologous CD19-Chimeric Antigen Receptor T cells (CAR T) Therapy, SLE and LN

CAB-201-001 Phase 1/2 Trial

Advisory/Clinical Services

Cullinan Therapeutics

CLN-978, a CD19xCD3 bispecific T cell engager

Phase 1b, SLE

Advisory/Clinical Services

GlaxoSmithKline

GSK4527363 (monoclonal antibody) and belimumab

GSK Study: 221458, Phase 1b, SLE

Clinical Services

Nkarta CAR NK

Allogeneic Chimeric Antigen Receptor Natural Killer Cells (CAR NK)

NKX019-102 Phase 1

Advisory/Clinical Services

Historical/Completed Studies

Study Name: ACE-2020

Phase 2, SLE

Enrollment Ended

Study Name: Adicet Bio

ADI-001 (Allogeneic Gamma Delta CAR T Cell Therapy)

Phase 1, SLE and LN

Clinical Services

Recruiting

Study Name: Amgen

Phase 2, SLE, LN

CD-19 Targeted T-cell Engager (TCE)

Phase 2, SLE/LN

Clinical Services

Enrollment Ended

Study Name: iCell Gene Therapeutics

Advisory Services

Recruiting

Study Name: Ventus c-GAS

cGAS/STING Inhibitor

Advisory Services

Recruiting

Study Name: Century Therapeutics CAR NK Cell Therapy

Clinical Services

Enrollment Ended

Study Name: GlaxoSmithKline

Clinical Services

Terminated

Study Name: Caribou Biosciences

Advisory/Clinical Services

Terminated

Study Name: Artiva Allogeneic NK

Clinical Services

Recruiting

Study Name: EMD Serono M5049 WILLOW

Enrollment Ended

Study Name: Fate Stem Cell Therapy

Induced Pluripotent Stem Cell (iPSC)

Advisory/Clinical Services

Recruiting

Study Name: RIFLE

Phase 4, SLE

Enrollment Ended

Study Name: Janssen LOTUS

Phase 3, SLE

Terminated

Study Name: UCB PHOENYCS GO

Phase 3, SLE

Enrollment Ended

Study Name: VeraTx COMPASS

Phase 3, LN

Terminated

Study Name: BMS Paisley SLE

Phase 2, SLE

Enrollment Ended

Study Name: AMG570

Phase 2, SLE

Terminated

Study Name: AMG592

Phase 2b, SLE

Terminated

Study Name: Celgene CC-220

Phase 2, SLE

Enrollment Ended

Study Name: EMD Serono M2591

Phase 2, SLE

Terminated

Study Name: Lilly BT01

Phase 2, SLE

Terminated

Study Name: Lilly ISLAND SLE (KFAJ)

Phase 2, SLE

Enrollment Ended

Study Name: VIB7734 RECAST SLE

Phase 2, SLE

Enrollment Ended

Study Name: Janssen Orchid

Phase 2, LN

Enrollment Ended

Study Name: BMS Paisley LN

Phase 2, LN

Enrollment Ended

Study Name: Gilead COSMIC

Phase 2, CLE

Recruiting

Study Name: TAK-079

Phase 1b, SLE

Enrollment Ended

Study Name: Aker-ORKIDS

Phase NA, SLE

Enrollment Ended

Study Name: DIVINE

Phase NA, LN

Enrollment Ended

Study Name: VALUE

Phase NA, SLE

Enrollment Ended