Current Partner Studies

Lupus Therapeutics has been involved in some of the most important breakthroughs in lupus research. And today, we’re helping to guide what we hope will be future breakthroughs.

Ongoing

Study Name: BMS-POETYK SLE 1 & 2

A Study to Evaluate Effectiveness and Safety of Deucravacitinib (BMS-986165) Compared With Placebo in Participants With Active Systemic Lupus Erythematosus (POETYK SLE-2)

23 LuCIN sites (U.S. and Canada)

Study Name: UCB

UCB Biopharma SRL

A Study to Evaluate the Efficacy and Safety of Dapirolizumab Pegol in Study Participants With Moderately to Severely Active Systemic Lupus Erythematosus (PHOENYCS GO)

25 LuCIN sites (U.S. and Canada)

Study Name: Lilly-KFAJ

Eli Lilly and Company

A Study of LY3471851 in Adults With Systemic Lupus Erythematosus (SLE) (ISLAND-SLE)

13 LuCIN sites (U.S. and Canada)

Study Name: VIB7734

Horizon Therapeutics

Study of VIB7734 for the Treatment of Moderate to Severely Active SLE (RECAST SLE)

7 LuCIN sites (U.S. and Canada)

Study Name: BIOGEN AMETHYST

Biogen

A Study to Assess the Efficacy and Safety of BIIB059 in Participants With Active Subacute Cutaneous Lupus Erythematosus (SCLE) and/or Chronic Cutaneous Lupus Erythematosus (CCLE) With or Without Systemic Manifestations and Refractory and/or Intolerant to Antimalarial Therapy (AMETHYST)

18 LuCIN sites (U.S. and Canada)

Study Name: BIOGEN TOPAZ

Biogen

A Study to Evaluate the Efficacy and Safety of BIIB059 in Adult Participants With Active Systemic Lupus Erythematosus Receiving Background Nonbiologic Lupus Standard of Care (TOPAZ-1)

21 LuCIN sites (U.S. and Canada)

Study Name: Lilly BT01

Eli Lilly and Company

A IMMA Master Protocol: A Study of LY3361237 in Participants With at Least Moderately Active Systemic Lupus Erythematosus

4 LuCIN sites (U.S. and Canada)

Study Name: VeraTx COMPASS

Vera Therapeutics

Atacicept in Subjects with Active Lupus Nephritis (COMPASS)

14 LuCIN sites (U.S. and Canada)

Study Name: Gilead COSMIC

Study of GS-5718 in Participants With Cutaneous Lupus Erythematosus (CLE)

Up to 10 LuCIN sites (U.S.)

Study Name: SIRIUS-SLE 1

Phase 3 study to evaluate two regimens of ianalumab on top of standard-of-care therapy in patients with systemic lupus erythematosus (SIRIUS-SLE 1)

Up to 20 LuCIN sites (U.S. & CAN)

Study Name: SIRIUS-SLE 2

Phase 3 study to evaluate ianalumab on top of standard-of-care therapy in patients with systemic lupus erythematosus (SIRIUS-SLE 2)

Up to 20 LuCIN sites (U.S. & CAN)

Study Name: SIRIUS-LN

Study of safety, efficacy and tolerability of ianalumab versus placebo, in combination with SoC therapy, in participants with active lupus nephritis

Up to 15 LuCIN sites (U.S. & CAN)

Past

Study Name: AKER-ORKIDS

Aker Biomarine Antarctic AS

Omega-3 Replacement With Krill Oil in Disease Management of SLE (ORKIDS)

22 LuCIN sites (U.S. and Canada)

Study Name: AMG570

Efficacy and Safety of AMG 570 in Subjects With Active Systemic Lupus Erythematosus (SLE)

16 LuCIN sites (U.S. and Canada)

Study Name: AMG592

Efficacy and Safety of Efavaleukin Alfa in Subjects With Active Systemic Lupus Erythematosus

10 LuCIN sites (U.S. and Canada)

Study Name: BMS-PAISLEY SLE

An Investigational Study to Evaluate BMS-986165 in Participants With Systemic Lupus Erythematosus

21 LuCIN sites (U.S. and Canada)

Study Name: CELGENE-CC-220

Bristol-Myers Squibb (Celgene)

A Study to Evaluate the Efficacy and Safety of CC-220 in Subjects With Active Systemic Lupus Erythematosus

23 LuCIN sites (U.S. and Canada)

Study Name: DIVINE

RILITE Foundation

Dynamic Imaging of Variation in Lupus Nephritis (DIVINE)

7 LuCIN sites (U.S. and Canada)

Study Name: JANSSEN ORCHID

Janssen Research & Development, LLC

A Study of Guselkumab in Participants With Active Lupus Nephritis (ORCHID-LN)

5 LuCIN sites (U.S. and Canada)

Study Name: RIFLE-PREDNISONE

Ampel BioSolutions, LLC

A Crossover Study to Compare RAYOS to IR Prednisone to Improve Fatigue and Morning Symptoms for SLE (RIFLE)

21 LuCIN sites (U.S. and Canada)

Study Name: TAKEDA-TAK-079

Takeda (Millennium Pharmaceuticals, Inc.)

A Study to Evaluate the Safety, Pharmacokinetics (PK), and Pharmacodynamics (PD) of TAK-079 in Combination With Standard Background Therapy in Participants With Moderate to Severe Systemic Lupus Erythematosus (SLE)

10 LuCIN sites (U.S. and Canada)

Study Name: VALUE-App

Pfizer

Validation of a Mobile Phone Based on EPRO Tool in Subjects With Systemic Lupus Erythematosus (VALUE)

10 LuCIN sites (U.S. and Canada)